Clinical and pathological profile of paraquat poisoning cases - A cross-sectional study in Odisha, India

نویسندگان

چکیده

Introduction: Agriculture being the primary mode of occupation in Odisha leads to rampant and widespread use chemical pesticides herbicides. Paraquat is a widely used herbicide. Ingestion PQ irrespective quantity could be fatal with life-threatening effects on gastrointestinal (GI) tract, kidney, liver, lungs, other organs. Death usually associated respiratory insufficiency due an oxidative insult Type-II alveolar epithelium subsequent fibrosis. Materials Methods: All cases paraquat ingestion coming AIIMS, Bhubaneswar casualty from July 2020 November were studied for their clinical findings. The subjected autopsy findings noted. Results: Men most commonly involved. patients had self-harm intent while consuming. common presenting symptoms difficulty swallowing, Respiratory system was affected. cause death attributed multi-organ failure. Discussion: marketed its efficacy low environmental toxicity. Lack specific antidote increases fatality. causes renal failure by causing hypovolemia, circulatory failure, septicemia, direct mainstay treatment supportive though immune-suppressants has shown some positive results. Keywords: Paraquat, Herbicide, Pulmonary fibrosis, Multi organ

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ژورنال

عنوان ژورنال: Indian journal of forensic and community medicine

سال: 2021

ISSN: ['2394-6768', '2394-6776']

DOI: https://doi.org/10.18231/j.ijfcm.2020.043